Is there a contact for the project (different from the PI)?
Yes No
Is this request a response to an FOA or program officer direction?
Yes No
What is the FOA/RFA number?
Is submission to NCRAD required by this FOA/RFA?
Yes No
Who is the program officer?
What is the full name of the study?
What is the study abbreviation?
Is this study already active?
Yes No
What is the proposed start date (with NCRAD)?
Today M-D-Y
What is the study duration?
In Years
How many sites will enroll?
How many sites are outside the United States?
Where are the International sites located?
How many participants will be enrolled total?
What is the participant recruitment criteria for your study?
What is the enrollment setting for your study?
Clarify "Other" enrollment setting
Demographics (race, ethnicity, years of education, ADI/RUCA) of recruitment catchment area
Anticipated race and ethnicity enrollment goals?
Anticipated enrollment goals by years of education (proportion above and below 12 years of education)
Anticipated enrollment goals of rural participants
How many participants will be enrolled in Year 1?
How many participants will be enrolled in Year 2?
How many participants will be enrolled in Year 3?
How many participants will be enrolled in Year 4?
How many participants will be enrolled in Year 5?
Total Participants in Year 1
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Total Participants in Year 2
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Total Participants in Year 3
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Total Participants in Year 4
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Total Participants in Year 5
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Is your study longitudinal?
Yes
No
Please fill in the number of participants expected to have a visit in each year: Visit Year 1 Year 2 Year 3 Year 4 Year 5 Baseline Total
Including baseline, how many visits will be conducted per participant?
Per participant
What is the time frame for the visits?
Monthly
Every 6 Months
Annual
Other
Are the same specimens collected at every visit?
Yes
No
What is the visit schedule?
How many participants will be enrolled in a Baseline Visit in Year 1?
How many participants will be enrolled in a Baseline Visit in Year 2?
How many participants will be enrolled in a Baseline Visit in Year 3?
How many participants will be enrolled in a Baseline Visit in Year 4?
How many participants will be enrolled in a Baseline Visit in Year 5?
How many participants will be enrolled in a Visit 2 in Year 1?
How many participants will be enrolled in a Visit 2 in Year 2?
How many participants will be enrolled in a Visit 2 in Year 3?
How many participants will be enrolled in a Visit 2 in Year 4?
How many participants will be enrolled in a Visit 2 in Year 5?
How many participants will be enrolled in a Visit 3 in Year 1?
How many participants will be enrolled in a Visit 3 in Year 2?
How many participants will be enrolled in a Visit 3 in Year 3?
How many participants will be enrolled in a Visit 3 in Year 4?
How many participants will be enrolled in a Visit 3 in Year 5?
How many participants will be enrolled in a Visit 4 in Year 1?
How many participants will be enrolled in a Visit 4 in Year 2?
How many participants will be enrolled in a Visit 4 in Year 3?
How many participants will be enrolled in a Visit 4 in Year 4?
How many participants will be enrolled in a Visit 4 in Year 5?
How many participants will be enrolled in a Visit 5 in Year 1?
How many participants will be enrolled in a Visit 5 in Year 2?
How many participants will be enrolled in a Visit 5 in Year 3?
How many participants will be enrolled in a Visit 5 in Year 4?
How many participants will be enrolled in a Visit 5 in Year 5?
How many participants will be enrolled in a Visit 6 in Year 1?
How many participants will be enrolled in a Visit 6 in Year 2?
How many participants will be enrolled in a Visit 6 in Year 3?
How many participants will be enrolled in a Visit 6 in Year 4?
How many participants will be enrolled in a Visit 6 in Year 5?
Total Participants in Year 1
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Total Participants in Year 2
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Total Participants in Year 3
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Total Participants in Year 4
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Total Participants in Year 5
View equation
Please fill in the names of the visits in the "Visit" column, and the number of participants expected to have a visit in each year in the "Years 1-5" columns:
Visit Year 1 Year 2 Year 3 Year 4 Year 5 Total
What sample types will be collected?
How much blood for DNA is expected to be collected from each participant at each visit?
How many buffy coat samples are expected from each participant at each visit?
typically one per EDTA tube processed for plasma
How many buffy coat aliquots will be transferred to NCRAD?
How many saliva samples (for DNA) are expected from each participant at each visit?
How frequently will DNA aliquots be transferred?
What size aliquots will be transferred to NCRAD? NCRAD typically requests at least 5ug.
Can NCRAD store and share any residual DNA?
Yes
No
How much blood for RNA is expected to be collected from each participant at each visit?
please note each PAXgene tube holds 2.5ml of blood
How much blood for plasma is expected to be collected from each participant at each visit?
What is the aliquot size?
If more than one size, check all that apply and explain below.
How many plasma aliquots will be transferred to NCRAD?
Please provide details on aliquots to be transferred
How much blood for serum is expected to be collected from each participant at each visit?
What is the aliquot size?
If more than one size, check all that apply and explain below.
How many serum aliquots will be transferred to NCRAD?
Please provide details on aliquots to be transferred
How much blood to send as unprocessed/frozen whole blood is expected to be collected from each participant at each visit?
How much CSF is expected to be collected from each participant at each visit?
What is the aliquot size?
If more than one size, check all that apply and explain below.
How many CSF aliquots will be transferred to NCRAD?
Please provide details on aliquots to be transferred
How much urine is expected to be collected from each participant at each visit?
What is the aliquot size?
If more than one size, check all that apply and explain below.
How many urine aliquots will be transferred to NCRAD?
Please provide details on aliquots to be transferred
How many saliva samples (not for DNA) are expected from each participant at each visit?
How many fecal samples are expected from each participant at each visit?
How much blood for PBMCs is expected to be collected from each participant at each visit?
if planning to make iPSCs, NCRAD recommends at least 2 x 10ml NaHep tubes
What other sample types do you wish to collect?
Other site/visit details or notes
Ex. CSF will be collected from 50% of participants.
Will you need collection kits from NCRAD?
Yes
No
Should NCRAD plan for any distributions?
Yes
No
What kind of distributions should NCRAD plan for?
Will NCRAD need to budget for any shipping expenses?
Yes
No
What kind of shipping expenses should NCRAD plan for?
Will you need biomarker assays run in the NCRAD Biomarker Assay Laboratory (BAL)?
Yes
No
Please complete the survey at this link.
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What is the final deadline for receiving the budget?
Today M-D-Y Please note that our standard turnaround is 10 business days.